Immunotherapy: A New Frontier in Cancer Treatment with Pharmacist Involvement

Immunotherapy represents a paradigm shift in cancer treatment by leveraging the body’s own immune system to fight cancer cells. Unlike chemotherapy, it offers a targeted, less toxic approach. Pharmacists, especially oncology pharmacists, play a critical role in the safe and effective delivery of these innovative treatments.

Pharmacists’ Key Roles in Immunotherapy:

• Compounding and verifying complex biologic agents.

• Monitoring immune-related adverse effects (IRAEs).

• Educating patients on drug interactions and symptom management.

• Adjusting doses based on patient immune response and lab data.

Main Immunotherapy Approaches:

• Checkpoint inhibitors: e.g., PD-1, PD-L1 blockers.

• CAR-T cell therapy: Requires trained pharmacist support.

• Monoclonal antibodies: Used in various cancers, requiring proper storage and handling.

FAQs

What are the most common side effects of immunotherapy?
They include fatigue, skin reactions, and autoimmune responses like colitis or pneumonitis.

How do pharmacists monitor patient outcomes in immunotherapy?
Through lab tests, side effect reports, and coordination with oncologists for dose or regimen adjustments.